Features a very low prospective for abuse relative to those in program 4. Features a currently acknowledged health care use in remedy in The usa. Abuse might bring on confined physical dependence or psychological dependence relative to Individuals in plan 4.
Walaupun kedua-dua colchicine dos tinggi dan rendah meningkatkan kejayaan rawatan jika dibandingkan dengan plasebo, colchicine dos tinggi (tetapi bukannya dos rendah) dapat meningkatkan jumlah peristiwa sampingan buruk berbanding dengan plasebo sementara jumlah peristiwa sampingan buruk mungkin serupa dalam perbandingan colchicine dos rendah dengan NSAID.
Colchicine adalah sejenis ubat yang selalunya digunakan dalam rawatan gout semasa serangan akut atau untuk mencegah serangan semasa memulakan terapi pengurangan asid urik.
The Nationwide Institute for Wellness and Social Care (Awesome) pointers for that diagnosis and management of gout emphasise the need for Health care professionals to interact with this issue and remain mindful of the latest evidence and procedure possibilities[three].
A next goal of gout therapy would be to convey down uric acid ranges about the long run to circumvent future attacks.
Gout is usually a sort of inflammatory arthritis. An assault might appear after an illness or injuries. The main signal is usually soreness in the massive toe. It always affects 1 joint at any given time, but gout can unfold to other joints and go away them hunting red and swollen.
Remember the fact that early prognosis and treatment method are vital to avoid gout assaults and prolonged-expression joint problems. Your healthcare provider can diagnose gout depending on uric acid amounts here within your blood or by making use of an X-ray or ultrasound.
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Kesan sampingan allopurinol termasuk ruam dan jumlah darah yang rendah. Kesan sampingan febuxostat pula termasuk ruam, mual, fungsi hati yang berkurangan dan peningkatan risiko kematian yang berkaitan dengan jantung.
Selain itu, anda juga boleh website jadikan timun sebagai pes untuk ditampal pada sendi yang bengkak dan sakit. Caranya:
Ubat kortikosteroid seperti ubat prednison, dapat mengawal keradangan dan sakit gout. Kortikosteroid sakit gout buku lali mungkin didapati dalam bentuk pil, atau boleh disuntik ke sendi anda.
Selain itu, febuxostat juga cenderung mencetuskan serangan gout pada kali pertama anda memakannya. Oleh itu, doktor secara amnya juga akan memberi anda NSAID atau colchicine yang rendah untuk dimakan selama enam bulan pertama ketika mula mengambil febuxostat.
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Colchicine interacts with other medicines damaged down through the liver enzyme cytochrome P450 3A4. A few examples contain statins, antifungals, and several heart medicines.